Pathological crystallization of human immunoglobulins
نویسندگان
چکیده
منابع مشابه
Pathological crystallization of human immunoglobulins.
Condensation of Igs has been observed in pharmaceutical formulations and in vivo in cases of cryoglobulinemia. We report a study of monoclonal IgG cryoglobulins overexpressed by two patients with multiple myeloma. These cryoglobulins form crystals, and we measured their solubility lines. Depending on the supersaturation, we observed a variety of condensate morphologies consistent with those rep...
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متن کامل9 Human Immunoglobulins
9.5 Range of Application, Dosage 9.5.1 Indications for Subcutaneous or Intramuscular Injection of Normal Immunoglobulins 9.5.2 Indications for Intravenous Injection of Normal Immunoglobulins 9.5.2.1 Primary Immunodeficiency Diseases 9.5.2.2 Secondary Immunodeficiency Diseases 9.5.2.3 High-Dose ivIg Treatment in Certain Autoimmune Diseases and Diseases of Unknown Etiology 9.5.3 Licensed Indicati...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2012
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1211723109